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Dabrafenib Promotes Schwann Cell Differentiation by Inhibition of the MEK-ERK Pathway

Schwann cell differentiation involves a dynamic interaction of signaling cascades. However, much remains to be elucidated regarding the function of signaling molecules that differ depending on the context in which the molecules are engaged. Here, we identified a small molecule, dabrafenib, which pro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Park, Kyuhee, Shin, Yoonkyoung, Lee, Gyeongbeen, Park, Hwantae, Choi, Yongmun
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8068149/
https://ncbi.nlm.nih.gov/pubmed/33917810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26082141
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