Successful Direct Acting Antiviral Therapy in Chronic Hepatitis C Normalizes IFNγ and IL2 Production in T Cells Together with TLR8 Expression and Functionality in Peripheral Blood Mononuclear Cells

Chronic hepatitis C infection (HCV) activates a systemic cell-mediated immune response characterized by the production of IFNγ and an innate immune response addressed by the activation of TLR signaling. We aimed to investigate whether HCV eradication by direct acting antivirals (DAA) leads to a reco...

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Udgivet i:Viruses
Main Authors: Arias-Loste, María Teresa, Cabezas, Joaquín, Llerena, Susana, Iruzubieta, Paula, San-Segundo, David, Merino, David, Cuadrado, Antonio, Vaqué, José Pedro, López-Hoyos, Marcos, Crespo, Javier
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8068025/
https://ncbi.nlm.nih.gov/pubmed/33917265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13040635
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