Increased Expression Profile and Functionality of TLR6 in Peripheral Blood Mononuclear Cells and Hepatocytes of Morbidly Obese Patients with Non-Alcoholic Fatty Liver Disease

Current evidence suggests that gut dysbiosis drives obesity and non-alcoholic fatty liver disease (NAFLD) pathogenesis. Toll-like receptor 2 (TLR2) and TLR6 specifically recognize components of Gram-positive bacteria. Despite the potential implications of TLR2 in NAFLD pathogenesis, the role of TLR6...

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Publicado no:Int J Mol Sci
Main Authors: Arias-Loste, María Teresa, Iruzubieta, Paula, Puente, Ángela, Ramos, David, Santa Cruz, Carolina, Estébanez, Ángel, Llerena, Susana, Alonso-Martín, Carmen, San Segundo, David, Álvarez, Lorena, López Useros, Antonio, Fábrega, Emilio, López-Hoyos, Marcos, Crespo, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133878/
https://ncbi.nlm.nih.gov/pubmed/27834919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17111878
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