Pt(IV) Prodrugs with NSAIDs as Axial Ligands

A chemo-anti-inflammatory strategy is of interest for the treatment of aggressive cancers. The platinum (IV) prodrug with non-steroidal anti-inflammatory drugs (NSAIDs) as axial ligands is designed to efficiently enter tumor cells due to high lipophilicity and release the cytotoxic metabolite and NS...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Spector, Daniil, Krasnovskaya, Olga, Pavlov, Kirill, Erofeev, Alexander, Gorelkin, Peter, Beloglazkina, Elena, Majouga, Alexander
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067705/
https://ncbi.nlm.nih.gov/pubmed/33917027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083817
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