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Phosphatidylinositol Stabilizes Fluid-Phase Liposomes Loaded with a Melphalan Lipophilic Prodrug

Previously, a liposomal formulation of a chemotherapeutic agent melphalan (Mlph) incorporated in a fluid lipid bilayer of natural phospholipids in the form of dioleoylglyceride ester (MlphDG) was developed and the antitumor effect was confirmed in mouse models. The formulation composed of egg phosph...

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Podrobná bibliografie
Vydáno v:Pharmaceutics
Hlavní autoři: Tretiakova, Daria, Le-Deigen, Irina, Onishchenko, Natalia, Kuntsche, Judith, Kudryashova, Elena, Vodovozova, Elena
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067299/
https://ncbi.nlm.nih.gov/pubmed/33915726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13040473
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