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Synthesis of Two Methotrexate Prodrugs for Optimizing Drug Loading into Liposomes
Methotrexate (MTX), a compound originally used as an anticancer drug, has also found applications in a broad variety of autoimmune disorders thanks to its anti-inflammation and immunomodulatory functions. The broad application of MTX is anyway limited by its poor solubility in biological fluids, its...
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| Vydáno v: | Pharmaceutics |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7998143/ https://ncbi.nlm.nih.gov/pubmed/33806703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13030332 |
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