Inhibition of the Receptor for Advanced Glycation End Products Enhances the Cytotoxic Effect of Gemcitabine in Murine Pancreatic Tumors

Pancreatic ductal adenocarcinoma (PDAC) remains a very difficult cancer to treat. Recent in vitro and in vivo studies suggest that the activation of the receptor for advanced glycation end products (RAGE) by its ligands stimulates pancreatic cancer cell proliferation and tumor growth. Additional stu...

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Pubblicato in:Biomolecules
Autori principali: Swami, Priyanka, O’Connell, Kelly A., Thiyagarajan, Swetha, Crawford, Ayrianne, Patil, Prathamesh, Radhakrishnan, Prakash, Shin, Simon, Caffrey, Thomas C., Grunkemeyer, James, Neville, Tammi, Vetter, Stefan W., Hollingsworth, Michael A., Leclerc, Estelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067004/
https://ncbi.nlm.nih.gov/pubmed/33915939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11040526
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