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Inhibition of the Receptor for Advanced Glycation End Products Enhances the Cytotoxic Effect of Gemcitabine in Murine Pancreatic Tumors

Pancreatic ductal adenocarcinoma (PDAC) remains a very difficult cancer to treat. Recent in vitro and in vivo studies suggest that the activation of the receptor for advanced glycation end products (RAGE) by its ligands stimulates pancreatic cancer cell proliferation and tumor growth. Additional stu...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Swami, Priyanka, O’Connell, Kelly A., Thiyagarajan, Swetha, Crawford, Ayrianne, Patil, Prathamesh, Radhakrishnan, Prakash, Shin, Simon, Caffrey, Thomas C., Grunkemeyer, James, Neville, Tammi, Vetter, Stefan W., Hollingsworth, Michael A., Leclerc, Estelle
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067004/
https://ncbi.nlm.nih.gov/pubmed/33915939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11040526
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