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In Vitro and In Vivo Efficacy of AZD3965 and Alpha-Cyano-4-Hydroxycinnamic Acid in the Murine 4T1 Breast Tumor Model

Monocarboxylate transporter 1 (MCT1) represents a potential therapeutic target in cancer. The objective of this study was to determine the efficacy of AZD3965 (a specific inhibitor of MCT1) and α-cyano-4-hydroxycinnamic acid (CHC, a nonspecific inhibitor of MCTs) in the murine 4T1 tumor model of tri...

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Detalles Bibliográficos
Publicado en:AAPS J
Main Authors: Guan, Xiaowen, Morris, Marilyn E.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8066402/
https://ncbi.nlm.nih.gov/pubmed/32529599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-020-00466-9
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