Carbon Nanotubes—Potent Carriers for Targeted Drug Delivery in Rheumatoid Arthritis

Two types of single-walled carbon nanotubes (SWCNTs), HiPco- and carboxyl-SWCNT, are evaluated as drug carriers for the traditional anti-inflammatory drug methotrexate (MTX) and a small interfering RNA (siRNA) targeting NOTCH1 gene. The nanotubes are solubilized by PEGylation and covalently loaded w...

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Udgivet i:Pharmaceutics
Main Authors: Kofoed Andersen, Camilla, Khatri, Sangita, Hansen, Jonas, Slott, Sofie, Pavan Parvathaneni, Rohith, Mendes, Ana C., Chronakis, Ioannis S., Hung, Shu-Chen, Rajasekaran, Narendiran, Ma, Zhuoran, Zhu, Shoujun, Dai, Hongjie, Mellins, Elizabeth D., Astakhova, Kira
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8066293/
https://ncbi.nlm.nih.gov/pubmed/33801590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13040453
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