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LOXL4 Abrogation Does Not Exaggerate Angiotensin II-Induced Thoracic or Abdominal Aortic Aneurysm in Mice

It has been shown that thoracic aortic aneurysm and dissection (TAAD) could be a Mendelian trait caused by a single gene mutation. The LOX gene mutation leads to the development of human TAAD. The LOXL4 gene is a member of the lysyl oxidase gene family. We identified seven variants in the LOXL4 gene...

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Dettagli Bibliografici
Pubblicato in:Genes (Basel)
Autori principali: Li, Huimin, Guo, Jun, Jia, Yiting, Kong, Wei, Li, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8066229/
https://ncbi.nlm.nih.gov/pubmed/33807332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12040513
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