Tumor–Stromal Interactions in a Co-Culture Model of Human Pancreatic Adenocarcinoma Cells and Fibroblasts and Their Connection with Tumor Spread

One key feature of pancreatic ductal adenocarcinoma (PDAC) is a dense desmoplastic reaction that has been recognized as playing important roles in metastasis and therapeutic resistance. We aim to study tumor–stromal interactions in an in vitro coculture model between human PDAC cells (Capan-1 or PL-...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Prieto-García, Elena, Díaz-García, C. Vanesa, Agudo-López, Alba, Pardo-Marqués, Virginia, García-Consuegra, Inés, Asensio-Peña, Sara, Alonso-Riaño, Marina, Pérez, Carlos, Gómez, Carlos, Adeva, Jorge, Paz-Ares, Luis, López-Martín, José A., Agulló-Ortuño, M. Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065458/
https://ncbi.nlm.nih.gov/pubmed/33807441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9040364
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