Tumor–Stromal Interactions in a Co-Culture Model of Human Pancreatic Adenocarcinoma Cells and Fibroblasts and Their Connection with Tumor Spread

One key feature of pancreatic ductal adenocarcinoma (PDAC) is a dense desmoplastic reaction that has been recognized as playing important roles in metastasis and therapeutic resistance. We aim to study tumor–stromal interactions in an in vitro coculture model between human PDAC cells (Capan-1 or PL-...

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Bibliographic Details
Published in:Biomedicines
Main Authors: Prieto-García, Elena, Díaz-García, C. Vanesa, Agudo-López, Alba, Pardo-Marqués, Virginia, García-Consuegra, Inés, Asensio-Peña, Sara, Alonso-Riaño, Marina, Pérez, Carlos, Gómez, Carlos, Adeva, Jorge, Paz-Ares, Luis, López-Martín, José A., Agulló-Ortuño, M. Teresa
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065458/
https://ncbi.nlm.nih.gov/pubmed/33807441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9040364
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