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Biphasic Production of Anti-ApoB100 Autoantibodies in Obese Humans and Mice

Obesity is associated with autoimmunity, a phenomenon considered as harmful. Here we show that obese mice and humans produce IgG-type autoantibodies that specifically recognize apolipoprotein B-100 (ApoB100), its native epitope p210, and the synthetic p210 mimotope pB1. By contrast, antibodies again...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Choe, Moon Kyung, Kim, Hyung-Ji, Kim, Nan Hee, Binas, Bert, Kim, Hyo Joon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065440/
https://ncbi.nlm.nih.gov/pubmed/33916621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14040330
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