RNA-induced liquid phase separation of SARS-CoV-2 nucleocapsid protein facilitates NF-κB hyper-activation and inflammation

The ongoing 2019 novel coronavirus disease (COVID-19) caused by SARS-CoV-2 has posed a worldwide pandemic and a major global public health threat. The severity and mortality of COVID-19 are associated with virus-induced dysfunctional inflammatory responses and cytokine storms. However, the interplay...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Signal Transduct Target Ther
Hlavní autoři: Wu, Yaoxing, Ma, Ling, Cai, Sihui, Zhuang, Zhen, Zhao, Zhiyao, Jin, Shouheng, Xie, Weihong, Zhou, Lingli, Zhang, Lei, Zhao, Jincun, Cui, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065320/
https://ncbi.nlm.nih.gov/pubmed/33895773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-021-00575-7
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky