RNA-induced liquid phase separation of SARS-CoV-2 nucleocapsid protein facilitates NF-κB hyper-activation and inflammation

The ongoing 2019 novel coronavirus disease (COVID-19) caused by SARS-CoV-2 has posed a worldwide pandemic and a major global public health threat. The severity and mortality of COVID-19 are associated with virus-induced dysfunctional inflammatory responses and cytokine storms. However, the interplay...

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Publicado no:Signal Transduct Target Ther
Main Authors: Wu, Yaoxing, Ma, Ling, Cai, Sihui, Zhuang, Zhen, Zhao, Zhiyao, Jin, Shouheng, Xie, Weihong, Zhou, Lingli, Zhang, Lei, Zhao, Jincun, Cui, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065320/
https://ncbi.nlm.nih.gov/pubmed/33895773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-021-00575-7
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