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Oxygen-independent disulfide bond formation in VEGF-A and CA9

Low levels of oxygen (hypoxia) occurs in many (patho)physiological situations. Adaptation to hypoxia is in part mediated by proteins expressed in the extracellular space that mature in the endoplasmic reticulum (ER) prior to traversing the secretory pathway. The majority of such ER cargo proteins re...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Levitin, Fiana, Lee, Sandy Che-Eun S., Hulme, Stephanie, Rumantir, Ryan A., Wong, Amy S., Meester, Marmendia R., Koritzinsky, Marianne
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065220/
https://ncbi.nlm.nih.gov/pubmed/33675747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100505
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