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Co-delivery of IOX1 and doxorubicin for antibody-independent cancer chemo-immunotherapy

Anti-programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) antibodies are currently used in the clinic to interupt the PD-1/PD-L1 immune checkpoint, which reverses T cell dysfunction/exhaustion and shows success in treating cancer. Here, we report a histone demethylase inhibitor, 5-c...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liu, Jing, Zhao, Zhihao, Qiu, Nasha, Zhou, Quan, Wang, Guowei, Jiang, Haiping, Piao, Ying, Zhou, Zhuxian, Tang, Jianbin, Shen, Youqing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065121/
https://ncbi.nlm.nih.gov/pubmed/33893275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22407-6
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