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How cyanophage S-2L rejects adenine and incorporates 2-aminoadenine to saturate hydrogen bonding in its DNA

Bacteriophages have long been known to use modified bases in their DNA to prevent cleavage by the host’s restriction endonucleases. Among them, cyanophage S-2L is unique because its genome has all its adenines (A) systematically replaced by 2-aminoadenines (Z). Here, we identify a member of the Prim...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Czernecki, Dariusz, Legrand, Pierre, Tekpinar, Mustafa, Rosario, Sandrine, Kaminski, Pierre-Alexandre, Delarue, Marc
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065100/
https://ncbi.nlm.nih.gov/pubmed/33893297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22626-x
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