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How cyanophage S-2L rejects adenine and incorporates 2-aminoadenine to saturate hydrogen bonding in its DNA

Bacteriophages have long been known to use modified bases in their DNA to prevent cleavage by the host’s restriction endonucleases. Among them, cyanophage S-2L is unique because its genome has all its adenines (A) systematically replaced by 2-aminoadenines (Z). Here, we identify a member of the Prim...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Czernecki, Dariusz, Legrand, Pierre, Tekpinar, Mustafa, Rosario, Sandrine, Kaminski, Pierre-Alexandre, Delarue, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065100/
https://ncbi.nlm.nih.gov/pubmed/33893297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22626-x
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