How cyanophage S-2L rejects adenine and incorporates 2-aminoadenine to saturate hydrogen bonding in its DNA

Bacteriophages have long been known to use modified bases in their DNA to prevent cleavage by the host’s restriction endonucleases. Among them, cyanophage S-2L is unique because its genome has all its adenines (A) systematically replaced by 2-aminoadenines (Z). Here, we identify a member of the Prim...

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Argitaratua izan da:Nat Commun
Egile Nagusiak: Czernecki, Dariusz, Legrand, Pierre, Tekpinar, Mustafa, Rosario, Sandrine, Kaminski, Pierre-Alexandre, Delarue, Marc
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065100/
https://ncbi.nlm.nih.gov/pubmed/33893297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22626-x
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