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Exceptional stability of a perilipin on lipid droplets depends on its polar residues, suggesting multimeric assembly
Numerous proteins target lipid droplets (LDs) through amphipathic helices (AHs). It is generally assumed that AHs insert bulky hydrophobic residues in packing defects at the LD surface. However, this model does not explain the targeting of perilipins, the most abundant and specific amphipathic prote...
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| 發表在: | eLife |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
eLife Sciences Publications, Ltd
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8064757/ https://ncbi.nlm.nih.gov/pubmed/33856341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61401 |
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