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Convergent and Divergent Mechanisms of Epileptogenesis in mTORopathies
Hyperactivation of the mechanistic target of rapamycin complex 1 (mTORC1) due to mutations in genes along the PI3K-mTOR pathway and the GATOR1 complex causes a spectrum of neurodevelopmental disorders (termed mTORopathies) associated with malformation of cortical development and intractable epilepsy...
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| Udgivet i: | Front Neuroanat |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8064518/ https://ncbi.nlm.nih.gov/pubmed/33897381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnana.2021.664695 |
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