Sodium activates human monocytes via the NADPH oxidase and isolevuglandin formation

AIMS: Prior studies have focused on the role of the kidney and vasculature in salt-induced modulation of blood pressure; however, recent data indicate that sodium accumulates in tissues and can activate immune cells. We sought to examine mechanisms by which salt causes activation of human monocytes...

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Veröffentlicht in:Cardiovasc Res
Hauptverfasser: Ruggeri Barbaro, Natalia, Van Beusecum, Justin, Xiao, Liang, do Carmo, Luciana, Pitzer, Ashley, Loperena, Roxana, Foss, Jason D, Elijovich, Fernando, Laffer, Cheryl L, Montaniel, Kim R, Galindo, Cristi L, Chen, Wei, Ao, Mingfang, Mernaugh, Raymond L, Alsouqi, Aseel, Ikizler, Talat A, Fogo, Agnes B, Moreno, Heitor, Zhao, Shilin, Davies, Sean S, Harrison, David G, Kirabo, Annet
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8064439/
https://ncbi.nlm.nih.gov/pubmed/33038226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvaa207
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