Orally Administered Bacillus Spores Expressing an Extracellular Vesicle-Derived Tetraspanin Protect Hamsters Against Challenge Infection With Carcinogenic Human Liver Fluke

BACKGROUND: The human liver fluke Opisthorchis viverrini is a food-borne trematode that causes hepatobiliary disease in humans throughout Southeast Asia. People become infected by consuming raw or undercooked fish containing metacercariae. Development of a vaccine to prevent or minimize pathology wo...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Phumrattanaprapin, Wuttipong, Chaiyadet, Sujittra, Brindley, Paul J, Pearson, Mark, Smout, Michael J, Loukas, Alex, Laha, Thewarach
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8064041/
https://ncbi.nlm.nih.gov/pubmed/32813017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa516
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