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Expanding the membrane-protein NMR toolkit
An NMR method to monitor conformational states of challenging large protein targets is described. The method, which can be used to evaluate distances between two labels and to measure conformational exchange rates, revealed an unanticipated outward-facing state in a glutamate transporter.
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| Publicado no: | Nat Chem Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8064024/ https://ncbi.nlm.nih.gov/pubmed/32665639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0597-7 |
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