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Clonal Evolution of a High-Grade Pediatric Glioma With Distant Metastatic Spread
OBJECTIVE: High-grade glioma (HGG) rarely spreads outside the CNS. To test the hypothesis that the lesions were metastases originating from an HGG, we sequenced the relapsing HGG and distant extraneural lesions. METHODS: We performed whole-exome sequencing of an HGG lesion, its local relapse, and di...
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| Publicado no: | Neurol Genet |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wolters Kluwer
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8063622/ https://ncbi.nlm.nih.gov/pubmed/33898738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000561 |
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