Clonal Evolution of a High-Grade Pediatric Glioma With Distant Metastatic Spread

OBJECTIVE: High-grade glioma (HGG) rarely spreads outside the CNS. To test the hypothesis that the lesions were metastases originating from an HGG, we sequenced the relapsing HGG and distant extraneural lesions. METHODS: We performed whole-exome sequencing of an HGG lesion, its local relapse, and di...

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Detaylı Bibliyografya
Yayımlandı:Neurol Genet
Asıl Yazarlar: Marinari, Eliana, Dutoit, Valerie, Nikolaev, Sergey, Vargas, Maria-Isabel, Schaller, Karl, Lobrinus, Johannes Alexander, Dietrich, Pierre-Yves, Tsantoulis, Petros, Migliorini, Denis
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wolters Kluwer 2021
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8063622/
https://ncbi.nlm.nih.gov/pubmed/33898738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000561
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