Quantification of B-cell maturation antigen, a target for novel chimeric antigen receptor T-cell therapy in Myeloma

B-cell maturation antigen (BCMA) is expressed by normal and malignant plasma cells and is targeted via anti-BCMA chimeric antigen receptor T-cell therapy (BCMA CAR T-cell therapy) in plasma cell myeloma (PCM) patients. Surface BCMA expression is required for CAR T-cell binding and killing. We determ...

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Publicado en:Leuk Res
Autores principales: Salem, Dalia A., Maric, Irina, Yuan, Constance M., Liewehr, David J., Venzon, David J., Kochenderfer, James, Stetler-Stevenson, Maryalice
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8063571/
https://ncbi.nlm.nih.gov/pubmed/30053652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2018.07.015
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