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moDCs differentiate into Bcl6(+) mature moDCs to promote cyclic di-GMP vaccine adjuvant-induced memory T(H) cells in the lung

Induction of lung mucosal immune responses is highly desirable for vaccines against respiratory infections. We recently showed that monocyte-derived DCs (moDCs) are responsible for lung IgA induction. However, the DC subset inducing lung memory T(H) cells is unknown. Here, using conditional knockout...

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Библиографические подробности
Опубликовано в: :J Immunol
Главные авторы: Mansouri, Samira, Katikaneni, Divya S, Gogoi, Himanshu, Jin, Lei
Формат: Artigo
Язык:Inglês
Опубликовано: 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8063211/
https://ncbi.nlm.nih.gov/pubmed/33879579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2001347
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