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MutSα mismatch repair protein stability is governed by subunit interaction, acetylation, and ubiquitination
In eukaryotes, DNA mismatch recognition is accomplished by the highly conserved MutSα (Msh2/Msh6) and MutSβ (Msh2/Msh3) complexes. Previously, in the yeast Saccharomyces cerevisiae, we determined that deleting MSH6 caused wild-type Msh2 levels to drop by ∼50%. In this work, we determined that Msh6 s...
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| Udgivet i: | G3 (Bethesda) |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8063085/ https://ncbi.nlm.nih.gov/pubmed/33793773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/g3journal/jkaa065 |
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