Genome-Wide Association Study of Non-syndromic Orofacial Clefts in a Multiethnic Sample of Families and Controls Identifies Novel Regions

Orofacial clefts (OFCs) are among the most prevalent craniofacial birth defects worldwide and create a significant public health burden. The majority of OFCs are non-syndromic and vary in prevalence by ethnicity. Africans have the lowest prevalence of OFCs (~ 1/2,500), Asians have the highest preval...

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Pubblicato in:Front Cell Dev Biol
Autori principali: Mukhopadhyay, Nandita, Feingold, Eleanor, Moreno-Uribe, Lina, Wehby, George, Valencia-Ramirez, Luz Consuelo, Muñeton, Claudia P. Restrepo, Padilla, Carmencita, Deleyiannis, Frederic, Christensen, Kaare, Poletta, Fernando A., Orioli, Ieda M., Hecht, Jacqueline T., Buxó, Carmen J., Butali, Azeez, Adeyemo, Wasiu L., Vieira, Alexandre R., Shaffer, John R., Murray, Jeffrey C., Weinberg, Seth M., Leslie, Elizabeth J., Marazita, Mary L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062975/
https://ncbi.nlm.nih.gov/pubmed/33898419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.621482
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