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Genome Wide Interaction Studies Identify Sex-Specific Risk Alleles for Nonsyndromic Orofacial Clefts

Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is the most common craniofacial birth defect in humans and is notable for its apparent sexual dimorphism where approximately twice as many males are affected as females. The sources of this disparity are largely unknown, but interactions b...

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Vydáno v:Genet Epidemiol
Hlavní autoři: Carlson, Jenna C., Nidey, Nichole L., Butali, Azeez, Buxo, Carmen J., Christensen, Kaare, Deleyiannis, Frederic W-D, Hecht, Jacqueline T., Field, L. Leigh, Moreno-Uribe, Lina M., Orioli, Ieda M., Poletta, Fernando A., Padilla, Carmencita, Vieira, Alexandre R., Weinberg, Seth M., Wehby, George L., Feingold, Eleanor, Murray, Jeffrey C., Marazita, Mary L., Leslie, Elizabeth J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6185762/
https://ncbi.nlm.nih.gov/pubmed/30277614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22158
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