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Molecular Chaperone GRP94/GP96 in Cancers: Oncogenesis and Therapeutic Target

During tumor development and progression, intrinsic and extrinsic factors trigger endoplasmic reticulum (ER) stress and the unfolded protein response, resulting in the increased expression of molecular chaperones to cope with the stress and maintain tumor cell survival. Heat shock protein (HSP) GRP9...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Duan, Xiaofeng, Iwanowycz, Stephen, Ngoi, Soo, Hill, Megan, Zhao, Qiang, Liu, Bei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062746/
https://ncbi.nlm.nih.gov/pubmed/33898309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.629846
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