Molecular basis of F-actin regulation and sarcomere assembly via myotilin

Sarcomeres, the basic contractile units of striated muscle cells, contain arrays of thin (actin) and thick (myosin) filaments that slide past each other during contraction. The Ig-like domain-containing protein myotilin provides structural integrity to Z-discs—the boundaries between adjacent sarcome...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Kostan, Julius, Pavšič, Miha, Puž, Vid, Schwarz, Thomas C., Drepper, Friedel, Molt, Sibylle, Graewert, Melissa Ann, Schreiner, Claudia, Sajko, Sara, van der Ven, Peter F. M., Onipe, Adekunle, Svergun, Dmitri I., Warscheid, Bettina, Konrat, Robert, Fürst, Dieter O., Lenarčič, Brigita, Djinović-Carugo, Kristina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062120/
https://ncbi.nlm.nih.gov/pubmed/33844684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001148
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