Molecular basis of F-actin regulation and sarcomere assembly via myotilin

Sarcomeres, the basic contractile units of striated muscle cells, contain arrays of thin (actin) and thick (myosin) filaments that slide past each other during contraction. The Ig-like domain-containing protein myotilin provides structural integrity to Z-discs—the boundaries between adjacent sarcome...

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Publicado en:PLoS Biol
Autores principales: Kostan, Julius, Pavšič, Miha, Puž, Vid, Schwarz, Thomas C., Drepper, Friedel, Molt, Sibylle, Graewert, Melissa Ann, Schreiner, Claudia, Sajko, Sara, van der Ven, Peter F. M., Onipe, Adekunle, Svergun, Dmitri I., Warscheid, Bettina, Konrat, Robert, Fürst, Dieter O., Lenarčič, Brigita, Djinović-Carugo, Kristina
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062120/
https://ncbi.nlm.nih.gov/pubmed/33844684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001148
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