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Metabolic engineering strategy for synthetizing trans-4-hydroxy-l-proline in microorganisms

Trans-4-hydroxy-l-proline is an important amino acid that is widely used in medicinal and industrial applications, particularly as a valuable chiral building block for the organic synthesis of pharmaceuticals. Traditionally, trans-4-hydroxy-l-proline is produced by the acidic hydrolysis of collagen,...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Zhang, Zhenyu, Liu, Pengfu, Su, Weike, Zhang, Huawei, Xu, Wenqian, Chu, Xiaohe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8061225/
https://ncbi.nlm.nih.gov/pubmed/33882914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-021-01579-2
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