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Targeting MCL-1 in cancer: current status and perspectives
Myeloid leukemia 1 (MCL-1) is an antiapoptotic protein of the BCL-2 family that prevents apoptosis by binding to the pro-apoptotic BCL-2 proteins. Overexpression of MCL-1 is frequently observed in many tumor types and is closely associated with tumorigenesis, poor prognosis and drug resistance. The...
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| Pubblicato in: | J Hematol Oncol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8061042/ https://ncbi.nlm.nih.gov/pubmed/33883020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-021-01079-1 |
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