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Radiochemical synthesis and evaluation in nonhuman primates of 3-[(11)C]methoxy-4-aminopyridine: a novel PET tracer for Imaging Potassium Channels in the CNS

Demyelination, the loss of the protecting sheath of neurons, contributes to disability in many neurological diseases. In order to fully understand its role in different diseases and to monitor treatments aiming at reversing this process, it would be valuable to have PET radiotracers that can detect...

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Bibliografiske detaljer
Udgivet i:ACS Chem Neurosci
Main Authors: Guehl, Nicolas J., Neelamegam, Ramesh, Zhou, Yu-Peng, Moon, Sung-Hyun, Dhaynaut, Maeva, Fakhri, Georges El, Normandin, Marc D., Brugarolas, Pedro
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060895/
https://ncbi.nlm.nih.gov/pubmed/33539063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00791
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