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Radiochemical synthesis and evaluation in nonhuman primates of 3-[(11)C]methoxy-4-aminopyridine: a novel PET tracer for Imaging Potassium Channels in the CNS

Demyelination, the loss of the protecting sheath of neurons, contributes to disability in many neurological diseases. In order to fully understand its role in different diseases and to monitor treatments aiming at reversing this process, it would be valuable to have PET radiotracers that can detect...

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Publicat a:ACS Chem Neurosci
Autors principals: Guehl, Nicolas J., Neelamegam, Ramesh, Zhou, Yu-Peng, Moon, Sung-Hyun, Dhaynaut, Maeva, Fakhri, Georges El, Normandin, Marc D., Brugarolas, Pedro
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060895/
https://ncbi.nlm.nih.gov/pubmed/33539063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00791
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