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Reproductive outcomes from maternal loss of Nlrp2 are not improved by IVF or embryo transfer consistent with oocyte-specific defect.

Nlrp2 encodes a protein of the oocyte subcortical maternal complex (SCMC), required for embryo development. We previously showed that loss of maternal Nlrp2 in mice causes subfertility, smaller litters with birth defects and growth abnormalities in offspring, indicating that Nlrp2 is a maternal effe...

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Dettagli Bibliografici
Pubblicato in:Reprod Sci
Autori principali: Arian, Sara, Rubin, Jessica, Chakchouk, Imen, Sharif, Momal, Mahadevan, Sangeetha K., Erfani, Hadi, Shelly, Katharine, Liao, Lan, Lorenzo, Isabel, Ramakrishnan, Rajesh, Van den Veyver, Ignatia B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060370/
https://ncbi.nlm.nih.gov/pubmed/33090377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s43032-020-00360-x
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