Reproductive outcomes from maternal loss of Nlrp2 are not improved by IVF or embryo transfer consistent with oocyte-specific defect.

Nlrp2 encodes a protein of the oocyte subcortical maternal complex (SCMC), required for embryo development. We previously showed that loss of maternal Nlrp2 in mice causes subfertility, smaller litters with birth defects and growth abnormalities in offspring, indicating that Nlrp2 is a maternal effe...

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Detalhes bibliográficos
Publicado no:Reprod Sci
Main Authors: Arian, Sara, Rubin, Jessica, Chakchouk, Imen, Sharif, Momal, Mahadevan, Sangeetha K., Erfani, Hadi, Shelly, Katharine, Liao, Lan, Lorenzo, Isabel, Ramakrishnan, Rajesh, Van den Veyver, Ignatia B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060370/
https://ncbi.nlm.nih.gov/pubmed/33090377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s43032-020-00360-x
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