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RNA binding of Hfq monomers promotes RelA-mediated hexamerization in a limiting Hfq environment

The RNA chaperone Hfq, acting as a hexamer, is a known mediator of post-transcriptional regulation, expediting basepairing between small RNAs (sRNAs) and their target mRNAs. However, the intricate details associated with Hfq-RNA biogenesis are still unclear. Previously, we reported that the stringen...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Basu, Pallabi, Elgrably-Weiss, Maya, Hassouna, Fouad, Kumar, Manoj, Wiener, Reuven, Altuvia, Shoshy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060364/
https://ncbi.nlm.nih.gov/pubmed/33883550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22553-x
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