Systemic delivery of targeted nanotherapeutic reverses angiotensin II-induced abdominal aortic aneurysms in mice

Abdominal aortic aneurysm (AAA) disease causes dilation of the aorta, leading to aortic rupture and death if not treated early. It is the 14th leading cause of death in the U.S. and 10th leading cause of death in men over age 55, affecting thousands of patients. Despite the prevalence of AAA, no saf...

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Vydáno v:Sci Rep
Hlavní autoři: Wang, Xiaoying, Parasaram, Vaideesh, Dhital, Saphala, Nosoudi, Nasim, Hasanain, Shahd, Lane, Brooks A., Lessner, Susan M., Eberth, John F., Vyavahare, Naren R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060294/
https://ncbi.nlm.nih.gov/pubmed/33883612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88017-w
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