Nanoparticle-based targeted delivery of pentagalloyl glucose reverses elastase-induced abdominal aortic aneurysm and restores aorta to the healthy state in mice

AIM: Abdominal aortic aneurysms (AAA) is a life-threatening weakening and expansion of the abdominal aorta due to inflammatory cell infiltration and gradual degeneration of extracellular matrix (ECM). There are no pharmacological therapies to treat AAA. We tested the hypothesis that nanoparticle (NP...

Full description

Saved in:
Bibliographic Details
Published in:PLoS One
Main Authors: Dhital, Saphala, Vyavahare, Naren R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7100957/
https://ncbi.nlm.nih.gov/pubmed/32218565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0227165
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items