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Type I Interferon in Chronic Virus Infection and Cancer

Type I interferons (IFN-Is) are emerging as key drivers of inflammation and immunosuppression in chronic infection. Control of these infections requires IFN-I signaling; however, prolonged IFN-I signaling can lead to immune dysfunction. IFN-Is are also emerging as double-edged swords in cancer, prov...

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Detalhes bibliográficos
Publicado no:Trends Immunol
Main Authors: Snell, Laura M., McGaha, Tracy L., Brooks, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8059441/
https://ncbi.nlm.nih.gov/pubmed/28579323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2017.05.005
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