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A powerful subset-based method identifies gene set associations and improves interpretation in UK Biobank
Tests of association between a phenotype and a set of genes in a biological pathway can provide insights into the genetic architecture of complex phenotypes beyond those obtained from single-variant or single-gene association analysis. However, most existing gene set tests have limited power to dete...
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| Pubblicato in: | Am J Hum Genet |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8059336/ https://ncbi.nlm.nih.gov/pubmed/33730541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2021.02.016 |
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