A Fast and Accurate Method for Genome-wide Scale Phenome-wide G × E Analysis and Its Application to UK Biobank

The etiology of most complex diseases involves genetic variants, environmental factors, and gene-environment interaction (G × E) effects. Compared with marginal genetic association studies, G × E analysis requires more samples and detailed measure of environmental exposures, and this limits the poss...

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Vydáno v:Am J Hum Genet
Hlavní autoři: Bi, Wenjian, Zhao, Zhangchen, Dey, Rounak, Fritsche, Lars G., Mukherjee, Bhramar, Lee, Seunggeun
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904814/
https://ncbi.nlm.nih.gov/pubmed/31735295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.10.008
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