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Trichostatin A preferentially reverses the upregulation of gene-expression levels induced by gain of chromosome 7 in colorectal cancer cell lines

Epithelial cancers are defined by a tumor-specific distribution of chromosomal aneuploidies that are maintained when cells metastasize and are conserved in cell lines derived from primary tumors. Correlations between genomic copy number and gene expression have been observed for different tumors inc...

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Veröffentlicht in:Genes Chromosomes Cancer
Hauptverfasser: Buishand, Floryne O., Cardin, Eric, Hu, Yue, Ried, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058626/
https://ncbi.nlm.nih.gov/pubmed/28940826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22505
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