Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the global COVID-19 pandemic. Rapidly-spreading SARS-CoV-2 variants may jeopardize newly-introduced antibody and vaccine countermeasures. Here, using monoclonal antibodies (mAbs), animal immune sera, human convalescent sera, and...

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Publicado no:Nat Med
Main Authors: Chen, Rita E., Zhang, Xianwen, Case, James Brett, Winkler, Emma S., Liu, Yang, VanBlargan, Laura A., Liu, Jianying, Errico, John M., Xie, Xuping, Suryadevara, Naveenchandra, Gilchuk, Pavlo, Zost, Seth J., Tahan, Stephen, Droit, Lindsay, Turner, Jackson S., Kim, Wooseob, Schmitz, Aaron J., Thapa, Mahima, Wang, David, Boon, Adrianus C.M., Presti, Rachel M., O’Halloran, Jane A., Kim, Alfred H.J., Deepak, Parakkal, Pinto, Dora, Fremont, Daved H., Crowe, James E., Corti, Davide, Virgin, Herbert W., Ellebedy, Ali H., Shi, Pei-Yong, Diamond, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058618/
https://ncbi.nlm.nih.gov/pubmed/33664494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-021-01294-w
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