IL-6 Signaling Mediates the Germinal Center Response, IgM Production and Nociceptive Sensitization in Male Mice after Tibia Fracture

BACKGROUND: Up-regulated interleukin 6 (IL-6) signaling, immune system activation, and pronociceptive autoantibodies are characteristic of complex regional pain syndrome (CRPS). IL-6 is known to promote B cell differentiation, thus we hypothesized that IL-6 signaling plays a crucial role in the deve...

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Publicado no:Brain Behav Immun
Main Authors: Li, Wen-Wu, Yang, Yang, Guo, Tian-Zhi, Sahbaie, Peyman, Shi, Xiao-you, Guang, Qin, Kingery, Wade S., Herzenberg, Leonore A., Clark, J. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058295/
https://ncbi.nlm.nih.gov/pubmed/33636311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2021.02.015
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