MM2‐Thalamic Creutzfeldt–Jakob Disease: Neuropathological, Biochemical and Transmission Studies Identify a Distinctive Prion Strain

In Creutzfeldt–Jakob disease (CJD), molecular typing based on the size of the protease resistant core of the disease‐associated prion protein (PrP(Sc)) and the M/V polymorphism at codon 129 of the PRNP gene correlates with the clinico‐pathologic subtypes. Approximately 95% of the sporadic 129MM CJD...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Moda, Fabio, Suardi, Silvia, Di Fede, Giuseppe, Indaco, Antonio, Limido, Lucia, Vimercati, Chiara, Ruggerone, Margherita, Campagnani, Ilaria, Langeveld, Jan, Terruzzi, Alessandro, Brambilla, Antonio, Zerbi, Pietro, Fociani, Paolo, Bishop, Matthew T., Will, Robert G., Manson, Jean C., Giaccone, Giorgio, Tagliavini, Fabrizio
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8057639/
https://ncbi.nlm.nih.gov/pubmed/22288561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00572.x
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